•It occurs world-wide with an estimated prevalence of 1
in 30–50 000. No data exists on prevalence in Nepal
•Case series of 19 patients has been published recently
(Nepal Journal of Neuroscience, Volume 1, Number 2, 2004)
•Certain features of Wilson's disease (WD) in Asia have
been found to be different from those in other continents.
•In many case series from india, this
disease is noted to manifest at a younger age in Indian children. The average
intake of copper in India ranges from 5.7-7.1 mg/day and is higher than the
reported 0.34-1.1 mg/day in Western countries. The practice of cooking food in
copper/copper alloy pots might be contributory.
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