•The clinical presentations
can be extremely varied viz: all forms of acute and chronic liver disease,
minimal to severe neurological disease,
psychiatric problems, bony deformities, hemolytic anemia and endocrine
manifestations.
•
•Age of presentation varies
from 4 to 60 years though majority present before the age of 30 years. The
younger the patient, the more likely is the hepatic involvement and after 20
years of age neurological symptoms predominate. KF ring may be absent in young
patient with liver disease but are always present in patient with neurological
symptoms.
•
•Untreated WD is uniformly
fatal. Death results from hepatic, renal, or hematological complications,
generally at the age of 30 years.
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•